Different HPV Vaccines |
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Dear Ask The Doctor: I heard there are 2 types of HPV vaccines available. What are the differences between the two HPV vaccines? Thank you. ........... Dear Gia: Human papillomavirus (HPV) can cause genital warts, cancer of the cervix, and various cancers of the vulva or vagina. Currently, more than 100 serotypes of HPV are described and more than 40 serotypes infect mucosal surfaces. The US Food and Drug Administration (FDA) has approved two HPV vaccines: 1.-Gardasil, is a quadrivalent HPV recombinant vaccine containing activity against HPV types 6, 11, 16, and 18. The vaccine is indicated for prevention of HPV-associated dysplasias and neoplasias, including cervical cancer, genital warts (condyloma acuminata), and precancerous genital lesions. The immunization series should be administered to girls and young women aged 9-26 years. It is administered as a series of 3 doses, typically at 0, 2, and 6 months; however, it is equally effective if all doses are given within 1 year. In October 2009, the Gardasil vaccine received FDA approval for the prevention of genital warts in men and boys. 2. - Cervarix is the second HPV vaccine and is also a recombinant formulation, was designed to create immunity against the L1 protein of HPV subtypes 16 and 18, which cause 70% of cervical cancer. It received FDA approval in September 2009. |
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| Last Updated ( Wednesday, 21 April 2010 ) |
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