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May 25, 2012
 

Unusual manifestations of glandular fever (Infectious Mononucleosis)

Dear Ask The Doctor: In February 2009 I had a severe case of mononucleosis. Since then I have been diagnosed with Pseudotumor Cerebri, Inappropriate Sinus Tachycardia, Orthostatic Hypotension, Right & Left Jugular vein stenosis (70% and 50% narrowed), Occipital Neuropathy, Anhidrosis, blood clotting problems, and have recently had enlargment of my right cervical lymph nodes. 3 were biopsied and were negative for a malignancy. I've lost 25 pounds and now weigh 105 and am 5 foot 6 inches. I am always tired. Do you have any ideas if this could all be connected? PLEASE HELP!

Dear Alli: Typical features of Infectious Mononucleosis (IM) include fever, inflammation of the pharynx, swollen lymph glands (nodes), fatigue, and atypical increased white blood cells in the blood. IM can be associated with various neurologic syndromes including; facial and other cranial nerve palsies, peripheral neuritis, and optic neuritis. Therefore I believe the occipital neuropathy could be related to IM. I cannot find any reports of a link between Pseudotumour cerebri and IM, but it has been linked with many systemic diseases including anaemia, therefore potentially possible. The causative virus Epstein Barr Virus(EBV) can affect virtually any organ system and has been associated with myocarditis, which could explain inappropriate Sinus Tachycardia. EBV infection can present with some unusual blood disorders including various types of anaemia, low platelets and blood clotting disorders. In summary the complications of this infection are wide and varied, and referral to a Haematologist may be appropriate if symptoms are not improving.

Last Updated ( Wednesday, 05 May 2010 )
 

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