Drugs mixed together for pain: Oxycodone and Indomethacine

Dear Ask The Doctor: Can oxycodon indomethicine be take together for pain

Dear Barry: Yes you could take them because they have two different action mechanisms: one is an anti-inflammatory medication (Indomethacine) and the other is a pain killer, but it is important that you know about the side effects of each one.Oxycodone is a potent analgesic (pain killer), that belongs to the opiate group of drugs, it is highly addictive, and the withdrawal symptoms are severe, such as fever, chills, insomnia, nausea, vomiting, diarrhea and muscle pain. In some cases, when use of the drug is stopped too abruptly, long-term users can even suffer convulsions. Also a Psychological dependency it is described after long-term use of hydrocodone. Attempts to stop using of the drug or lowering regular doses can cause intense cravings. Indomethacine as the rest of non-steroidal anti-inflammatories including Aspirin, may produce an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, epigastric pain, heartburn, diarrhea, abdominal distress, nausea and vomiting, indigestion, constipation, abdominal cramps or pain, fullness of GI tract (bloating and flatulence) and also kidney problems. These events can occur at any time during the drug use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal events. In controlled clinical trials the percentage of patients reporting one or more gastrointestinal complaints ranged from 4% to 16%.