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May 26, 2012
 

Side Effects of Too much Pradaxa?

Dear Ask The Doctor: I am a 34 year old athletic female and I have been on pradaxa for about 12 days now. I was prescribed 150mg 2 times a day for a month post heart ablation surgery. I had lone afib prior to the surgery and was a pretty intensive runner. Prior to surgery my blood pressure was around 102-68 and resting hr about 58-62. Since the surgery my blood pressure is 145-85 and my hr stays around 85-120. I am tired and winded constantly. I have had several headaches followed by nose bleeds and I hear this is normal on a blood thinner., however I am not finding anywhere that says this is "normal". I am also feeling light headed and dizzy most of the time. Is this the medication or is it a side effect of the surgery? I am having a hard time finding accurate answers on the internet. When I called the dr office, their resolution was to rest for 3 more weeks. From every surgical site I am seeing this is not a normal reaction to the surgery.. so I am thinking maybe side effect of the meds???

Dear Bran: Pradaxa (Dabigatran) is an anticoagulant, thrombin inhibitor that thins the blood to prevent clots from forming. It is prescribed for nonvalvular atrial fibrillation to prevent stroke and systemic embolism.

The side effects of the drug include :

i) Dyspepsia : Abdominal discomfort seen in 11% cases.

ii) Minor bleeding is seen in 8-33% and severe cases of bleeding is <6%.

iii) Other effects include anemia, allergic edema, anaphylaxis, bloody discharge, ecchymosis, epistaxis, hemarthrosis, hemorrhage (catheter site, hemorrhoidal, incision site, rectal), pruritus, rash, thrombocytopenia and urticaria.

Your symptoms of nose bleed could certainly be due to the drug. I would advise you to consult your doctor to rule out anemia that could cause a feeling light headedness and dizziness.

Last Updated ( Tuesday, 03 January 2012 )
 

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