Early pregnancy? When to see a doctor

Patient : Hi, I came off the pill a couple of months ago. I had a withdraw bleed and a month later a period. I had intercourse a few times around the time of ovulation. I was due to start my period on the 19th and am 4 days late. I have done 4 home pregnancy tests (two of the early) another on the day my period was due and another 3 days after my period due, all negative. I have the last few days being feeling tired, mild back pain, breasts seem enlarged and some stomach cramping. When should I take another pregnancy test? And if that again is negative when should I see doctor for a blood test? Many thanks
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