Elevated thyroglobulin level


Q: My 16 year old daughter's blood test came back with an elevated level of Thyroglobulins (it was 52 and they doctor said it should be 30). Is this a concern at all for thyroid cancer?


A:   Thyroglobulin is a protein produced and used by the thyroid gland to make the thyroid hormones thyroxine (T4) and triiodothyronine (T3). An isolated elevated thyroglobulin level is of limited significance, if all thyroid function tests are within the normal range, and your daughter is asymptomatic. Thyroglobulin levels in the blood can be elevated in cases of Graves' disease, an autoimmune thyroid disease. They can also be used as a tumor marker for certain kinds of thyroid cancer, and to monitor response to treatment. Patients with Hashimoto's thyroiditis or Graves' disease may develop antibodies against Thyroglobulin, known as anti-thyroglobulin antibodies. Some patients who are healthy also test positive for one or more thyroid antibodies and these findings tend to be higher in women and increased age. I would discuss the elevated thyroglobulin level result with your daughter’s family physician. This result must be interpreted in the correct clinical context, with the presence of relevant symptoms and abnormal thyroid function testing.

Related Q&A

Q: For a few years now I have been feeling very ill and gaining lots of weight. Hypothyroidism runs in my family but eve...

Q: 47 year old male high blood pressure little anxiety, for a about a month know I have gotten eczema on my hands that c...

Q: For years I have taken Llevothyroxine at a 0.125 daily dose and I was getting along fine with that dose for a period ...

Q: I was asked to get a series of tests done after complaining about allergy symptoms, i.e. swollen lips and hives. Doct...

Q: Started taking levothyroxine 50mg a day had awful side effects, all the symptoms of pms no periods these stopped, wen...


Dr. James Obaji M.D.

  • 247 Reviews
  • Family Physician

Dr. Suneel Sharman M.D.

  • 190 Reviews
  • Family Physician

Dr. Pat Golden M.D.

  • 169 Reviews
  • Cardiologist

Dr. Kunaal Jindal M.D.

  • 112 Reviews
  • Plastic Surgeon