Thyroglobulin is a protein produced and used by the thyroid gland to make the thyroid hormones thyroxine (T4) and triiodothyronine (T3). An isolated elevated thyroglobulin level is of limited significance, if all thyroid function tests are within the normal range, and your daughter is asymptomatic. Thyroglobulin levels in the blood can be elevated in cases of Graves' disease, an autoimmune thyroid disease. They can also be used as a tumor marker for certain kinds of thyroid cancer, and to monitor response to treatment. Patients with Hashimoto's thyroiditis or Graves' disease may develop antibodies against Thyroglobulin, known as anti-thyroglobulin antibodies. Some patients who are healthy also test positive for one or more thyroid antibodies and these findings tend to be higher in women and increased age. I would discuss the elevated thyroglobulin level result with your daughter’s family physician. This result must be interpreted in the correct clinical context, with the presence of relevant symptoms and abnormal thyroid function testing.
These Q&A’s are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.