Have questions relating to my 89 year old mother who
Patient :Have questions relating to my 89 year old mother who had reoccurring bladder infections for over 5 years. Was on preventative antibiotics such as nitro with elevated liver enzymes etc.
Anyhow - she had apprx 4 utis a year.
About half a year ago - she began 2000mg daily mannose sugar and has been uti free.
See uro study below
I believe for her its been effective. She historically has suffered from ecoli causing her incontinence, urgency and pain.
However, I just wanted to know the loading a sugar like this might have on the kidneys..
She began the sugar in April and 2.5 months later, her lab test
showed eGFR of 65 and creatinine of 71 (range of 60 -115)
Her CBC and urine tests were normal and the sugar is not metabolized in the body.
Deeming that the sugar comes from a good supplier - and contaminant free - how DOES one guage that the 2000mg daily wont cause taxing to the kidneys?
Please provide a succinct accurate answer showing some knowledge in this area or payment will be refuted
D mannose is a natural sugar as you know and has few side effects like diarrhea.
The upper limit dose is not specified clearly but in the research paper quoted by you, the dose is 2000 mg per day and the research was done for 6 months and at the end of it there was no alarming side effect in the patients.
In the absence of detailed studies, some doctors recommend taking d mannose in a dose of 500 mg twice daily for longer durations.
If kidney function tests are not showing any specific abnormal kidney function test results then 2000 mg d mannose daily has not caused any kidney associated dysfunction in your mother when she took it for 2 1/2 months.
It is important to know that since d mannose is a natural sugar therefore it is less likely to cause any kidney problems unless taken many times over recommended dose and over a longer duration.
I am sorry to state that an accurate answer is not available in context to consuming d mannose in recommended doses and kidney dysfunction however eGFR and creatinine are recommended tests for kidney function analysis.
It is important to know that GFR will decrease in the elderly population over 70 years and is a physiological variation.
Hope I could answer at least a part of your query.
Please do write back if you have any doubts.
These Q&A’s are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.