How does this result tell if my son is SS or AS


Q: My 2 year old son was recently diagnosed with sickle cell anemia. This prompted the necessity for all the family to do hemoglobin electrocytises. This test revealed that my husband, two of our kids and me are all carriers of the hbs. Now my question is what is the level of severity of my son's condition if his result shows 44% of HBA1 and 52% of HBS and 2.5 of HBA2 does this mean he is a carrier of 2 pairs of our ss genes or just one like his 2 other brothers. THanks, Zainab


A:   In order to be HbSS ie homozygous( contains both the pairs of genes ) one needs to have HbS of more than 80%. Since your son has HbS of 52% and HbA1 of 44% means that he is a heterozygote ie has only one pair of the genes. Thus he will be normal most of his life expect when and if he is exposed to conditions which lead to hypoxia ( ie decreased oxygen carrying capacity of the blood) . I hope this helps.

Related Q&A

Q: I'm just looking for info on some lab results. Below low ferratin levels. Low mcv,mch,mchc and high rdw levels mean.

Q: Hello Dr actually I did marriage tests so I got a high level of hba2 : 7.5  so the hematologist told me that I ...

Q: Hello Doctor I did a marriage test so it shows in the results that i have thalassemia minor as a carrier. But my fia...

Q: Hi, I have a history of low iron and borderline anemia, but it has been progressively worsening over the last year...

Q: Wondering if you can tell me if lab results are norm for CBC w/diff


Dr. James Obaji M.D.

  • 247 Reviews
  • Family Physician

Dr. Suneel Sharman M.D.

  • 190 Reviews
  • Family Physician

Dr. Pat Golden M.D.

  • 169 Reviews
  • Cardiologist

Dr. Kunaal Jindal M.D.

  • 112 Reviews
  • Plastic Surgeon