Knee Pain, prednisone

Patient : I have been on prednisone for 2 weeks for a UC flair. Things have been getting better in that regard but this morning I awoke with knee pain and upon trying to get out of bed was met with excruciating pain as if my knee's would break under my weight. I am 43 years old, weigh 180 and stand 5'10" tall. What would cause this and will it pass or should I seek medical attention?
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