Liver cirrhosis may decrease fertility


Q: I have been battling Primary Sclerosing Cholangitus, PSC, for 4 years now. I have chirossis of the Liver and Ulcerative cholitis. My Wife and I are trying to concive our first child, with no luck. We are tracking BMTs and Periods, making sure to have sex on high fertility days and ovulation days. I am wondering if the fact that my semen is jaundice looking, or yellowish in color. at one point it was orange, but that cleared up. Is this caused by my liver disease and will it prevent us from having children?


A:   Primary sclerosing cholangitis (PSC) and ulcerative colitis (UC) may not have a direct effect on your fertility; however various hormonal disturbances are often observed in patients with liver cirrhosis. Clinical features of male cirrhotic patients may include: gynaecomastia (breast enlargement in males), testicular wasting, reduced fertility, loss of libido, and impotence. Sex hormones may show a decrease in serum testosterone levels and an increase in serum oestrogen levels accompanied by an increase in the ratio of oestrogen to testosterone in patients with severe liver cirrhosis, depending on the severity of liver dysfunction. I would recommend referral to an OBGYN who specialises in fertility issues for individual advice in your case.

Related Q&A

Q: Hi Doctor; my girlfriend and I have been having sex for the past 3 days, we live in different countries so we hardly ...

Q: I had sex with a guy on the 20th. pulled out and did not cum in me. Had sex with another guy on the 23rd 25 26 27 28....

Q: I have a callus like thing on my right foot (bottom). It's extremely painful to walk. I have been using callus remove...

Q: Hello, first time on this site for me. I have a situation where my boyfriend got drunk for the first time with a neig...

Q: My girlfriend had hand foot mouth and it spread to her vagina. This was two months almost 3 months ago and since the...


Dr. James Obaji M.D.

  • 247 Reviews
  • Family Physician

Dr. Suneel Sharman M.D.

  • 190 Reviews
  • Family Physician

Dr. Pat Golden M.D.

  • 169 Reviews
  • Cardiologist

Dr. Kunaal Jindal M.D.

  • 112 Reviews
  • Plastic Surgeon