Melatonin with pain meds


Q: Can i take melatonin with hydromorpine and gralise? I have not been sleeping the past few weeks

Symptoms:  Not sleeping

A:   Hi,
Welcome to ATD.
Thanks for your query.

There are no known drug interactions / advrse effects by using melatonin and hydromorphone or gralise together. They can be taken together but some precautions need to be followed as both( hydromorphone & melatonin) increase drowsiness and sedation.

You should avoid or limit the use of alcohol while being treated with these medications.

Avoid driving or operating hazardous machinery until you know how the medications affect you.

I don't know the cause for your insomnia or the need for opiods, but these are among the best drugs you can get for your symptoms. In addition to the drugs you can also try if possible the following advice:

Guided visualization meditation
Progressive muscle relaxation
Deep breathing exercises
Mindfulness meditation

You can follow any of these methods which helps, depending on you capability and condition. It would be better to consult an Insomnia Expert to know the cause behind your sleeplessness and guide you with the required form of treatment with or without medications.

Hope this helps.
All the best.

Related Q&A

Q: Hi am having trouble getting to sleep as my chest is tight,cant get my breath,peak flows are no higher than 250 &...

Q: I took 6 unisom pills by accident. I have taken 3 before i forgot and took another 3.

Q: Hello i got qestion i gave my 3 months old by mistake first dafence nose spray instead of the baby water spray , what...

Q: Iv snorted approx 2g of coke not really strong stuff. Av took a Buspar am prescribed can I take sum Trazodone for sle...

Q: I have problems staying asleep at night. This is mostly due to work anxiety. I fall asleep just fine around 10:30pm b...


Dr. James Obaji M.D.

  • 247 Reviews
  • Family Physician

Dr. Suneel Sharman M.D.

  • 190 Reviews
  • Family Physician

Dr. Pat Golden M.D.

  • 169 Reviews
  • Cardiologist

Dr. Kunaal Jindal M.D.

  • 112 Reviews
  • Plastic Surgeon