Missed Period

Patient: The first day of my last period was on October 22nd. My normal menstrual cycle is 22-24 days apart. Ive never missed a period in my life since Ive started it at age 13. Iam now 25 years old. I had unprotected sex with my boyfriend three times from about November 5th-9th. No period yet and I took two home pregnancy test that came out negative. I don’t know whats going on here? Could this be pregnancy? The only type of symptoms Iam having is extreme fatigue, headaches, sore breast, and a little cramping.