Patient: I recently saw an article about across the counter pain medications could cause heart troubles. I take one Tylenol PM each night to help me go to sleep. I’m 66 years old…will this cause me ill effects?
Doctor: Tylenol PM contains acetaminophen and diphenhydramine. Acetominophen is safe in cardiovascular disease but diphenhydrami ne should be used with caution in patients with cardiovascular disease (including high blood pressure and ischemic heart disease).With reference to your other medications, Mobic (Meloxicam) and other non-selective NSAID’s, have been proven to have several adverse effects on the cardiovascular system, including interference with the beneficial antiplatelet activity of aspirin, an increase in cardiovascular events (including heart attack), and exacerbation of heart failure. Therefore unless this medication is absolutely necessary I would discontinue or reduce dose to the occasional or alternate days.