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I believe your wife is undergoing medical abortion with misoprostol alone. With 2 tabs of the drug , the bleeding was likely to occur and it should initiate uterine contraction causing some amount of pain as the uterus would push out the products of conception.
It is advisable that you report to the physician for a supervised medical abortion as there are chances of incomplete abortion and a check ultrasound is required to confirm completion. As far as pain relief is concerned , it can be advised at the ER and in the form of an injectable.
I hope i have answered your query,
wishing good health,
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