Patient: I am a 25yr old woman who weighs 290. I have worked out off and on ever since I was 16. On very often occasions when I work out I get this painful tingling feeling in my skin; in the ares where I hold the most weigh. It is painful, uncomfortable and I have no idea what causes this. I read it could be from tobacco smoking. FYI: I am not a tobacco smoker nor does the work out have to be extremely long before this painful tingling kicks in.