Pernicious anemia is a autoimmune disorder, in which certain gastric cell like parietal cells are destroyed. These cells help in absorption on Vitamin B12. In the disorder, since B12 can not be adsorbed, its deficiency sets in resulting in large red blood cell, which are fragile leading to megaloblastic anemia. As such pernicious anemia is not completely curable, as the cell can not be restored. But few vitamin supplements which given in other routes other than oral, since it cannot be absorbed, will keep a check on the disease. Few oral drugs are available which help in absorption of vitamin B12 are also choice of treatment, but as such the disease can not be completely cured, but can be controlled.
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