Profuse Sweating and Shivering - Serotonin Syndrome
Patient : I have problems where at night time i am sweating so bad when i get up the following morning my bed is drenched..but during the night i am freezing. this has been going on for nearly year...my husband says during the night i am so hot he cant sleep in the same bed as me ..i have been to my drs who says its a virus..how can a virus last year. please can you help im desperate for an answer chris smirk
In my opinion there is a possibilty of interaction between your current medications trazodone and venlafaxine, as theyey both have serotonergic activity, and together they may produce what is called a serotonin syndrome, which occur with concomitant use of serotonergic drugs.
These drugs can be used with caution if potential benefit is deemed to outweigh the risk. Patients should be closely monitored for symptoms of the serotonin syndrome during treatment like tachycardia, hyperthermia, shivering, blood pressure lability; neuromuscular abnormalities such as hyperreflexia, myoclonus, tremor, rigidity, and ataxia; and gastrointestinal symptoms such as abdominal cramping, nausea, vomiting, and diarrhea. You smay consult your doctor to explore the possibility of the serotonin syndrome, in which case you may have to reduce the dose or stop the drug to control the symptoms.
These Q&A’s are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.