Safe pregnancy

Patient : I am 32 & my wife is 28. We are not cousins. We had four kids alive. My wife had twin baby girls in May 2013. The elder twin girl at the age of 8 months diagnosed as pre-B A.L.L (leukemia) & died at the age of 9 months coz doctors refused to give chemotherapy to a child less than one year. Now my wife is pregnant again. I want your advise what precautions/test should I adopt to ensure no more babies could suffer from such a cursed illnesses.
Symptoms:  Pregnant with previous history of pre-B (A.L.L - leukemia) in one of the twins
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