Spider bite over 24 hours ago and my symptoms have worsen.

Patient

Q: Hi. I got bit over 24 hours by what appears to be a spider. The area around the bite mark is really swollen, itchy and painful. I cleaned the area, applied an anti-itch cream and took Loratadine this morning. Is there anything else I can do and when should I worry about it?
Thank you!

Symptoms:  Pain, swollen hand around the area where I got bit, fatigue
Doctor

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