Symptoms associated with an elevated serum prolactin

Patient : My breasts are leaking. I have not had my period in three months. A pregnancy test is negative. What can be the problem?
Doctor :   The symptoms you describe, leaking breasts, absence of periods, with a negative pregnancy test, may be due to an imbalan ce in your prolactin hormone levels. Prolactin hormone stimulates the female breast to produce milk, and it is secreted from the posterior pituitary gland. High prolactin hormone levels are common in pregnancy, post nipple stimulation and stress but many drugs can cause an elevated prolactin level. Atypical antipsychotic drugs e.g. Respiridone (Risperdal), antidepressant drugs e.g. Clomipramine (Anafranil), and gastrointestinal drugs e.g. Cimetidine (Tagamet) or Metoclopramide (Reglan) all elevate prolactin levels, mainly by blocking of Dopamine D2 receptors. Less common causes of high prolactin levels include pituitary tumours which secrete excess prolactin. In your case it is most likely a drug side-effect, therefore I would advise attending your family physician for prescription of a suitable alternative.

Related Q&A

Q: Are you able to look at a photo of my friends lower body - and tell me if you see any worrying skin areas - such as e...

Q: I fave a few small blood blister type bumps on the edge of the head of my penis. Can't figure out what it is called. ...

Q: Hi. I am a 56 yr old female. I went to the doctor because I was having a little discharge, no noticeable odor, (to me...

Q: I have a red patch beneath the penile head under the foreskin, and there is a red spot at the lower end of the penile...

Q: Hi Doctor, I am 37 year old male and I have been in a relationship for 7 years. I had an sti test at the start of the...


Dr. James Obaji M.D.

  • 247 Reviews
  • Family Physician

Dr. Suneel Sharman M.D.

  • 190 Reviews
  • Family Physician

Dr. Pat Golden M.D.

  • 169 Reviews
  • Cardiologist

Dr. Kunaal Jindal M.D.

  • 112 Reviews
  • Plastic Surgeon