Patient :Throughout the past 16 years I have been on 6 different antidepressants. Paxil (for 12 years had to be taken off because of weight gain) Zoloft (worked only 2 years) lexipro (worked only 2 years) Effexor (got symptoms back and because of blood pressure had to go off) then tapered to Prozac (did not work) and now celexa. I am truly scared. I am getting CBT finally, but hoping the celexa will work. I read on-line that when a person has been on a lot of antidepressants, changes are they will not work. Is that true? Where the paxil, zoloft, lexipro and effexor worked for a time, do you think celexa has a chance.
Thank you for your query at AskTheDoctor.com
I understand your concern.
No, because you have used other anti-depressants before, there is no reason why Celexa won't work for you.
The same drug can fail after a few months or years because of tolerance but you are switching to Celexa which is also considered to be superior to the other anti-depressants. Along with CBT it will definitely help you.
Please feel free to discuss further,
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