Tretinoin - what could have happened?

Patient : Hello, I have a question regarding the use of "Retin-A Gel 0.025%" (Tretinoin) acne cream. My wife is pregnant. First day of her last period was July 21. Conception could have only occurred between July 26 - 31 inclusive. My wife applied Retin-A Gel on the evenings (before sleep) of July 21, 22, 23, 24, 25 and on August 19. She has not and will not use Retin-A Gel again during this pregnancy. Could any adverse effect have been caused to our unborn baby? Thank you.
Doctor :   This question is currently in queue and will be answered shortly by one of our doctors. In the meantime you may browse our library of answered questions by clicking here.

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