Trisomy18 negative and trisomy21 Positive

Patient : Dear Doctor, My Self Prem,My wife is pregnant and 27 weeks now,We did first trimester scan and blood screen during Week 12 scan and screen test(trisomy18 negative) shows that the baby is normal and in second trimester we did anomaly scan and triple blood screen test.In scan it was normal and in screening it was Trisomy 21 positive.Our Dr referred Genetic counseling there that took one more scan and concluded that the 2nd trimester screen test would have been false positive as growth of the baby is normal and no soft markers found.My question is which screen report is more reliable 1st or 2nd.Kindly suggest.
Symptoms:  Pregnant
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