There are many causes for lower limb oedema (fluid). This can be a normal finding such as dependant oedema after a long-haul flight or oedema due to premenstrual or pregnancy hormones. It can be a result of certain drug therapies including calcium channel blockers, NSAIDs and oestrogens. However it can also be indicative of many disease states including thyroid disease particularly hypothyroidism; heart, kidney or liver failure; low protein levels due to malnutrition or nephrotic syndrome; diabetes mellitus; and inflammation or infection of the lower limbs. I would advise attending your family doctor for a full history, physical examination and appropriate treatment of the underlying cause to improve symptoms.
These Q&A’s are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.