Patient: Wasn’t sure which category to use…I’ve been on the Pill before and a few different prescriptions to find one. My problem is that I have PMS (which includes irritability and sometimes depression).When I’m on a new Pill for the month prior to my first period everything works wonderfully. My breasts get larger and my PMS is not there. However, the second month, my breast shrink and my PMS come back. Why is that and how can I stop that from happening? It is not a sensitivity as I’ve had them tested.