Wifes symtomes

Patient: My wife has puffy areas that so up randomly they are painful but only last about 12 to 24 hrs .they apppear to be some type of hard not under the skinshe has no brusing but somtimes fells like they burst.we have had them xrayed no blockage was shown. She is worried about bloodclots her twin died of a massive heart attack. she was tolded he had thromebosis.what action could i take to ease her mind??