Will smoking pot affect me when on pristiq and seropuel

Patient: Hey my name is mitchell, ive just been put on pristiq of a morning for depression and seroquel of a night because i was going days with out sleeping but i also smoke weed of a night i just would like to know if its safe to do that ive been smoking weed for 2 years of a night before i got put on these pills. thank you.

Doctor: