Worst case of back pain and weight loss ever?

Patient : If someone is experiencing chronic back pain, is very underweight and malnourished (looks like a skeleton), has very low muscle tone, cannot eat without throwing up, what should one do? Neither prescription drugs nor marijuana will help with anything. I checked with doctors, who are unsure about this condition and nearly clueless. What do you think is going on with this person's body?
Symptoms:  Very severe back pain (possible S -shape on back), nausea with vomiting, malnutrition, excessive weight loss, loss of appetite, very low muscle tone, loose bones.
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